If you wish to play in every key, one can always come to a seminar. I am one who basically believes in one chromatic in C.
That said, if you wish to get certain chords, or certain patterns in D minor, C minor, E minor, G or F Major, you should choose those patterns. Always choose the easiest way to play something so that you can concentrate on emotion and not technique. Change the key of the song to facilitate using those patterns not only because harmonicas are expensive, but also to get you more familiar with the patterns of one instrument. This way if there are more complicated chords or key areas in a song, or if it modulates, you still have one instrument and you expanded your technique.
If you stop thinking of positions and start thinking of keys by practicing the scales and arpeggios in D minor, C minor, E minor, G or F Major, this will be a big first step toward freedom.
Harmonically yours,
Robert Bonfiglio
http://www.robertbonfiglio.com
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